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1.
ACS Pharmacol Transl Sci ; 4(3): 1075-1078, 2021 Jun 11.
Article in English | MEDLINE | ID: covidwho-1233688

ABSTRACT

In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/PI3K/PTEN genes.

2.
ACS Pharmacol Transl Sci ; 4(1): 396-399, 2021 Feb 12.
Article in English | MEDLINE | ID: covidwho-989686

ABSTRACT

Cancer patients contracting SARS-CoV-2 encounter additional challenges due to inflammatory bursts and lymphopenia, which may aggravate breast cancer prognosis. In this in silico analysis, we identified the potential of miRNAs as new therapeutic targets to treat breast cancer patients infected with COVID-19 via the regulation of ADAM17 and EGFR expression microRNAs.

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